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Upingbio
SKU(재고 관리 코드):YP-Ab-17990-100UL
SMURF1 rabbit pAb
SMURF1 rabbit pAb
- Gene Name: SMURF1 KIAA1625
- Immunogen: Synthesized peptide derived from human SMURF1
- Specificity: This antibody detects endogenous levels of SMURF1 at Human, Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS . Plays a role in dendrite formation by melanocytes .
- Species: Human;Mouse
- Range: WB
- Protein: E3 ubiquitin-protein ligase SMURF1 (hSMURF1) (EC 6.3.2.-) (SMAD ubiquitination regulatory factor 1) (SMAD-specific E3 ubiquitin-protein ligase 1)
- DA: 83kD
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