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Upingbio
SKU(재고 관리 코드):YP-Ab-18051-100UL
UXT rabbit pAb
UXT rabbit pAb
- Gene Name: UXT HSPC024
- Immunogen: Synthesized peptide derived from human UXT
- Specificity: This antibody detects endogenous levels of UXT at Human,Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: Involved in gene transcription regulation . Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription . Together with URI1, associates with chromatin to the NKX3-1 promoter region . Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm . May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity . Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling . Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC . Suppresses cell transformation and it might mediate
- Species: Human;Rat
- Range: WB
- Protein: Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein)
- DA: 17kD
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