1
/
의
1
Upingbio
SKU(재고 관리 코드):YP-Ab-18086-100UL
SCUBE3 rabbit pAb
SCUBE3 rabbit pAb
- Gene Name: SCUBE3 CEGF3
- Immunogen: Synthesized peptide derived from human SCUBE3
- Specificity: This antibody detects endogenous levels of SCUBE3 at Human, Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: Is a positive regulator of the BMP signaling pathway, required for proper chondrogenesis, osteogenesis and skeletal development. It acts as coreceptor for BMP ligands, particularly BMP2 and BMP4, facilitating their interactions with BMP type I receptors . It is required for ligand-induced recruitment of BMP receptors to lipid rafts (By similarity). Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
- Species: Human;Mouse
- Range: WB
- Protein: Signal peptide, CUB and EGF-like domain-containing protein 3
- DA: 109kD
Share
