• PELI2 rabbit pAb
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Upingbio

YP-Ab-18123-100UL

PELI2 rabbit pAb

PELI2 rabbit pAb

Size
  • Gene Name: PELI2
  • Immunogen: Synthesized peptide derived from human PELI2
  • Specificity: This antibody detects endogenous levels of PELI2 at Human, Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
  • Species: Human;Mouse
  • Range: WB
  • Protein: E3 ubiquitin-protein ligase pellino homolog 2 (Pellino-2) (EC 6.3.2.-)
  • DA: 46kD
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