• PDE8A rabbit pAb
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Upingbio

YP-Ab-18177-100UL

PDE8A rabbit pAb

PDE8A rabbit pAb

Size
  • Gene Name: PDE8A
  • Immunogen: Synthesized peptide derived from human PDE8A
  • Specificity: This antibody detects endogenous levels of PDE8A at Human, Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes . May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development . Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling . Protects against cell death induced by hydrogen peroxide and staurosporine .
  • Species: Human;Mouse
  • Range: WB
  • Protein: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17)
  • DA: 91kD
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