ZnT-4 Polyclonal Antibody

Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g. MIM 114852), alkaline phosphatases (e.g. MIM 171760), various dehydrogenases, and superoxide dismutases (e.g. MIM 147450). SLC30A4 (solute carrier family 30 member 4), or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop.

The ZnT-4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ZnT-4 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

ZnT-4, also known as SLC30A4, is a member of the solute carrier family and plays a crucial role in zinc homeostasis. It is primarily expressed in the mammary gland, prostate, and intestine, where it facilitates the transport of zinc ions across cellular membranes. Dysregulation of ZnT-4 has been implicated in various diseases, including breast cancer and prostate cancer.

The ZnT-4 Polyclonal Antibody exhibits outstanding performance in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of ZnT-4 protein, displaying minimal cross-reactivity with related proteins. This antibody enables precise and accurate quantification of ZnT-4 expression, allowing researchers to gain valuable insights into its functional role and potential therapeutic implications.

With its high affinity and specificity, the ZnT-4 Polyclonal Antibody offers researchers a reliable tool for investigating the intricate mechanisms underlying zinc homeostasis and its impact on various physiological and pathological processes. Its exceptional performance and versatility make it an indispensable asset in the field of molecular biology and biomedical research.

Order the ZnT-4 Polyclonal Antibody today and unlock new possibilities in your research endeavors. Trust in its exceptional quality and performance to advance your understanding of zinc transport and its implications in health and disease.